The Journal of Pain
Volume 6, Issue 9 , Pages 581-587 , September 2005

Association Between Regional Idiopathic Neuropathy and Salivary Involvement as the Possible Mechanism for Oral Sensory Complaints

  • Michal Granot

      Affiliations

    • Faculty of Social Welfare and Health Studies, University of Haifa, Haifa, Israel
    • Department of Neurology, Rambam Medical Center and Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel
  • ,
  • Rafael M. Nagler

      Affiliations

    • Department of Oral & Maxillofacial Surgery, Oral Biochemistry Laboratory and Salivary Clinic, Rambam Medical Center and Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel
    • Corresponding Author InformationAddress reprint requests to Dr. R. M. Nagler, 17 Yaara Street, Timrat 23840, Israel

Received 19 December 2004 ,Accepted 21 March 2005.

References 

  1. Ben Aryeh H , Gottlieb I , Ish-Shalom S , David A , Szargel H , Laufer D . Oral complaints related to menopause . Maturitas . 1996;24:185–189
  2. Bergdahl J , Anneroth G , Perris H . Personality characteristics of patients with resistant burning mouth syndrome . Acta Odontol Scand . 1995;53:7–11
  3. Bergdahl M , Bergdahl J . Burning mouth syndrome (prevalence and associated factors) . J Oral Pathol Med . 1999;28:350–354
  4. Bergdahl M , Bergdahl J . Perceived taste disturbance in adults (prevalence and association with oral and psychological factors and medication) . Clin Oral Investig . 2002;6:145–149
  5. Bogetto F , Maina G , Ferro G , Carbone M , Gandolfo S . Psychiatric comorbidity in patients with burning mouth syndrome . Psychosom Med . 1998;60:378–385
  6. Chen Q , Samaranayake LP . Growth of the fungal pathogen Candida in parotid saliva of patients with burning mouth syndrome . Microbios . 2000;102:45–52
  7. Derogatis LR , Cleary PA . Factorial invariance across gender for the primary symptom dimensions of the SCL-90 . Br J Soc Clin Psychol . 1977;716:347–356
  8. Derogatis LR , Melisaratos N . The brief symptom inventory (an introductory report) . Psychol Med . 1983;13:595–605
  9. Fantasia J . Diagnosis and treatment of common oral lesions found in the elderly . Dent Clin North Am . 1997;41:877–890
  10. Femiano F , Gombos F , Scully C , Busciolano M , Luca PD . Burning mouth syndrome (BMS) (controlled open trial of the efficacy of alpha-lipoic acid (thioctic acid) on symptomatology) . Oral Dis . 2000;6:274–277
  11. Femiano F , Scully C , Gombos F . Idiopathic dysgeusia; an open trial of alpha lipoic acid (ALA) therapy . Int J Oral Maxillofac Surg . 2002;31:625–628
  12. Forssell H , Jaaskelainen S , Tenovuo O , Hinkka S . Sensory dysfunction in burning mouth syndrome . Pain . 2002;99:41–77
  13. Glick D , Ben-Aryeh H , Gutman D , Szargel R . Relation between idiopathic glossodynia and salivary flow rate and content . Int J Oral Surg . 1976;5:161–165
  14. Gorsky M , Silverman S , Chinn H . Clinical characteristics and management outcome in the burning mouth syndrome. An open study of 130 patients . Oral Surg Oral Med Oral Pathol . 1991;72:192–195
  15. Graven-Nielsen T, Jansson Y, Segerdahl M, Kristensen JD, Mense S, Arent-Nielsen L, et al. Experimental pain by ischaemic contractions compared with pain by intramuscular infusions of adenosine and hypertonic saline . Eur J Pain . 2003;7:93–102
  16. Grinspan D , Fernandez Blanco G , Allevato MA , Stengel FM . Burning mouth syndrome . Int J Dermatol . 1995;34:483–487
  17. Grushka M , Sessle BJ , Howley TP . Psychophysical evidence of taste dysfunction in burning mouth syndrome . Chem Senses . 1986;11:485–498
  18. Grushka M . Clinical features of burning mouth syndrome . Oral Surg Oral Med Oral Pathol . 1987;63:30–36
  19. Grushka M , Sessle BJ , Howley TP . Psychophysical assessment of tactile, pain and thermal sensory functions in burning mouth syndrome . Pain . 1987;28:169–184
  20. Grushka M , Sessle BJ . Taste dysfunction in burning mouth syndrome . Gerodontics . 1998;4:256–258
  21. Grushka M , Sessle BJ . Burning mouth syndrome . Dent Clin North Am . 1991;35:171–184
  22. Grushka M , Epstein J , Mott A . An open-label, dose escalation pilot study of the effect of clonazepam in burning mouth syndrome . Oral Surg Oral Med Oral Pathol Oral Radiol . 1998;86:557–561
  23. Grushka M , Epstein JB , Gorsky M . Burning mouth syndrome . Am Fam Physician . 2002;65:615–620
  24. Hardt J , Gerbershagen HU , Franke P . The symptom check-list SCL-90-R (its use and characteristics in chronic pain patients) . Eur J Pain . 2000;4:137–148
  25. Ito M , Kurita K , Ito T , Arao M . Pain threshold and pain recovery after experimental stimulation in patients with burning mouth syndrome . Psychiatr Clin Neurosci . 2002;56:161–168
  26. Jaaskelainen SK, Rinne JO, Forssell H, Tenuvuo O, Kaasinen V, Sonninen P, et al. Role of the dopaminergic system in chronic pain—a fluorodopa-PET study . Pain . 2001;90:257–260
  27. Lamey PJ , Lamb AB . Prospective study of etiological factors in burning mouth syndrome . Br Med J . 1988;296:1243–1246
  28. Lamey PJ , Murray BM , Eddie SA , Freeman RA . The secretion of parotid saliva as stimulated by 10% citric acid is not related to precipitating factors in burning mouth syndrome . J Oral Pathol Med . 2001;30:121–124
  29. Lamey PJ . Burning mouth syndrome . Dermatol Clin . 1996;4:339–354
  30. Lauritano D , Spadari F , Formaglio F , Zambellini Artini M , Salvato A . Etiopathogenic, clinical-diagnostic and therapeutic aspects of the burning mouth syndrome. Research and treatment protocols in a patient group . Minerva Stomatol . 1998;47:239–251
  31. Mancini G , Carbonara AD , Heremans JF . Immunochemical quantitation of antigens by single radial immunodiffusion . Immunochemistry . 1965;2:235–254
  32. Markley EJ , Mattes-Kulig D , Henkin RI . A classification of dysgeusia . J Am Diet Assoc . 1983;83:578–580
  33. Miyamoto SA , Ziccardi VB . Burning mouth syndrome . Mt Sinai J Med . 1998;65:343–347
  34. Nagler R , Marmary Y , Krausz Y , Chisin R , Markitziu A , Nagler A . Salivary gland dysfunction in human acute and chronic graft versus host disease (GVHD) . Bone Marrow Transplant . 1996;17:219–224
  35. Nagler RM , Hershkovich O , Lischinsky S , Diamond E , Reznick AZ . Saliva analysis in the clinical setting (revisiting an underused diagnostic tool) . J Investig Med . 2002;50:214–225
  36. Nagler RM , Klein I , Zarzhevsky N , Drigues N , Reznick AZ . Characterization of the differentiated antioxidant profile of human saliva . Free Radic Biol Med . 2002;32:268–277
  37. Nagler RM , Salameh F , Reznick AZ , Nahir M . Salivary glands involvement in rheumatoid arthritis and its relation to the induced oxidative stress . Rheumatology . 2003;42:1–8
  38. Nagler RM , Hershkovich O . Sialochemical and gustatory analysis in patients with oral sensorial complaints . J Pain . 2004;5:56–63
  39. Nicholson M , Wilkinson G , Field E , Longman L , Fitzgerald B . A pilot study (stability of psychiatric diagnoses over 6 months in burning mouth syndrome) . J Psychosom Res . 2002;49:1–2
  40. Pajukoski H , Meurman JH , Halonen P , Sulkava R . Prevalence of subjective dry mouth and burning mouth syndrome in hospitalized elderly patients and outpatients in relation to saliva, medication and systemic diseases . Oral Surg Oral Med Oral Pathol Oral Radiol . 1992;92:641–649
  41. Pisanty S , Rafaely B , Polishuk WZ . The effect of steroid hormones on buccal mucosa of menopausal women . Oral Surg Oral Med Oral Pathol . 1975;40:346–353
  42. Rojo L , Silvestre FJ , Bagan VJ , Vincente T . Prevalence of psychopathology in BMS. A comparative study among patients with and without psychiatric disorders and controls . Oral Surg Oral Med Oral Pathol . 1994;78:312–316
  43. Spielberger CD . Current Trends in Theory and Research on Anxiety . New York, NY: Academic Press; 1972; pp 3–19
  44. Sardella A , Uglietti D , Demarosi F , Lodi G , Bez C , Carrassi A . Benzydamine hydrochloride oral rinses in management of burning mouth syndrome. A clinical trial . Oral Surg Oral Med Oral Pathol Oral Radiol . 1999;88:683–686
  45. Schumacher MA , Jong BE , Frey SL , Sudangunta SP , Capra NF , Levine JD . The stretch-inactivated channel, a vanilloid receptor variant, is expressed in small-diameter sensory neurons in the rat . Neurosci Lett . 2002;287:215–228
  46. Spielman AI . Chemosensory function and dysfunction . Crit Rev Oral Biol Med . 1998;9:267–291
  47. Spielman AI . Interaction of saliva and taste . J Dent Res . 1990;69:838–843
  48. Teichman Y , Malineck F . Manual for the Hebrew State-Trait Anxiety Inventory . Tel-Aviv, Israel: Tel-Aviv University Press; 1978;
  49. Trikkas G , Nikolatou O , Samara C , Bazopoulou-Kyrkanidou E , Rabavilas AD , Christodoulou GN . Glossodynia (personality characteristics and psychopathology) . Psychother Psychosom . 1996;65:163–168
  50. Woda A , Navez ML , Picard P , Gremeau C , Pichard-Leandri E . A possible therapeutic solution for stomatodynia (burning mouth syndrome) . J Orofac Pain . 1998;12:272–278

PII: S1526-5900(05)00593-6

doi: 10.1016/j.jpain.2005.03.010

The Journal of Pain
Volume 6, Issue 9 , Pages 581-587 , September 2005