The Journal of Pain
Volume 7, Issue 10 , Pages 735-746 , October 2006

Design and Characterization of a Noncompetitive Antagonist of the Transient Receptor Potential Vanilloid Subunit 1 Channel With In Vivo Analgesic and Anti-inflammatory Activity

  • Carolina García-Martínez

      Affiliations

    • Instituto de Biología Molecular y Celular, Universidad Miguel Hernández, Alicante, Spain
    • ,
  • Asia Fernández-Carvajal

      Affiliations

    • Instituto de Biología Molecular y Celular, Universidad Miguel Hernández, Alicante, Spain
    • ,
  • Belen Valenzuela

      Affiliations

    • División de Farmacia y Tecnología Farmacéutica, Dpto Ingeniería, Universidad Miguel Hernández, Alicante, Spain
    • ,
  • Ana Gomis

      Affiliations

    • Instituto de Neurociencias, Universidad Miguel Hernández-CSIC, Alicante, Spain
    • ,
  • Wim Van Den Nest

      Affiliations

    • DiverDrugs, SL, Gavà, Barcelona, Spain
    • ,
  • Stefano Ferroni

      Affiliations

    • Department of Human and General Physiology, University of Bologna, Bologna, Italy
    • ,
  • Cristina Carreño

      Affiliations

    • DiverDrugs, SL, Gavà, Barcelona, Spain
    • ,
  • Carlos Belmonte

      Affiliations

    • Instituto de Neurociencias, Universidad Miguel Hernández-CSIC, Alicante, Spain
    • ,
  • Antonio Ferrer-Montiel

      Affiliations

    • Instituto de Biología Molecular y Celular, Universidad Miguel Hernández, Alicante, Spain
    • Corresponding Author InformationAddress reprint requests to Antonio Ferrer-Montiel, MD, Instituto de Biología Molecular y Celular, Universidad Miguel Hernández, Ed. Torregaitán, Av de la Universidad s/n, 03202 Elche (Alicante), Spain.

Received 1 December 2005 ,Revised 14 March 2006 ,Accepted 27 March 2006.

To access this article, please choose from the options below

Login to an existing account or Register a new account.

  • Purchase this article for 31.50 USD (You must login/register to purchase this article)

    Online access for 24 hours. The PDF version can be downloaded as your permanent record.

  • Subscribe to this title

    Get unlimited online access to this article and all other articles in this title 24/7 for one year.

  • Claim access now

    For current subscribers with Society Membership or Account Number.

  • Visit SciVerse ScienceDirect to see if you have access via your institution.

 Supported by grants from the Ministerio de Educacion Ciencia y Deporte (SAF 2003/0509), La Fundación Ramón Areces (01/08-500), and Generalitat Valenciana (GV04B-0398) to A.F.M., PROFIT-090000-2001-70 and CDTI-03-006 (Ministerio de Industria) to DiverDrugs, SL.

PII: S1526-5900(06)00686-9

doi: 10.1016/j.jpain.2006.03.008

The Journal of Pain
Volume 7, Issue 10 , Pages 735-746 , October 2006

Article Tools

* Image Usage & Resolution