The Journal of Pain
Volume 10, Issue 2 , Pages 167-172 , February 2009

A Prolonged Nitric Oxide-Dependent, Opioid-Mediated Antinociceptive Effect of Hyperbaric Oxygen in Mice

  • Lisa M. Zelinski

      Affiliations

    • Department of Pharmaceutical Sciences, College of Pharmacy, Pullman, Washington
    • ,
  • Yusuke Ohgami

      Affiliations

    • Department of Pharmaceutical Sciences, College of Pharmacy, Pullman, Washington
    • ,
  • Eunhee Chung

      Affiliations

    • Department of Pharmaceutical Sciences, College of Pharmacy, Pullman, Washington
    • ,
  • Donald Y. Shirachi

      Affiliations

    • Chico Hyperbaric Center, Chico, California
    • ,
  • Raymond M. Quock

      Affiliations

    • Department of Pharmaceutical Sciences, College of Pharmacy, Pullman, Washington
    • Center for Integrated Biotechnology, Washington State University, Pullman, Washington
    • Corresponding Author InformationAddress reprint requests to Dr. Raymond M. Quock, Department of Pharmaceutical Sciences, College of Pharmacy, Washington State University, PO Box 646534, Pullman, WA 99164

Received 10 June 2008 ,Revised 7 August 2008 ,Accepted 16 August 2008.

References 

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  2. Cahill FJ, Ellenberger EA, Mueller JL, Tseng LF, Quock RM. Antagonism of nitrous oxide antinociception in mice by intrathecally administered opioid peptide antisera. J Biomed Sci. 2000;7:299–303
  3. Chung E, Burke B, Bieber AJ, Doss JC, Ohgami Y, Quock RM. Dynorphin-mediated antinociceptive effects of l-arginine and SIN-1 (an NO donor) in mice. Brain Res Bull. 2006;70:245–250
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 Supported by National Institutes of Health Grant GM-77153 (R.M.Q.) and funds from the WSU College of Pharmacy, the Allen I. White Distinguished Professorship, and the Chico Hyperbaric Center.

 None of the authors have a conflict of interest in this work.

PII: S1526-5900(08)00715-3

doi: 10.1016/j.jpain.2008.08.003

The Journal of Pain
Volume 10, Issue 2 , Pages 167-172 , February 2009

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