« Previous
Next »
The Journal of Pain
Volume 11, Issue 4
, Pages 321-329
, April 2010
Differential Roles of Peripheral Metabotropic Glutamate Receptors in Bee Venom-Induced Nociception and Inflammation in Conscious Rats
References
- . Inflammation persistently enhances nocifensive behaviors mediated by spinal group I mGluRs through sustained ERK activation. Pain. 2004;111:125–135
- . Role of peripheral group I and II metabotropic glutamate receptors in IL-1beta-induced mechanical allodynia in the orofacial area of conscious rats. Pain. 2005;118:53–60
- . Peripheral group I metabotropic glutamate receptors modulate nociception in mice. Nat Neurosci. 2001;4:417–423
- . Peripheral excitatory amino acids. Curr Opin Pharmacol. 2001;1:52–56
- . Colocalization of metabotropic glutamate receptors in rat dorsal root ganglion cells. J Comp Neurol. 2007;501:780–789
- . Localization of metabotropic glutamate receptors 2/3 on primary afferent axons in the rat. Neuroscience. 2001;105:957–969
- . Differential roles of peripheral MAPK signal transduction pathways in bee venom-induced nociception and inflammation in conscious rats. J Pain. 2009;10:201–207
- . Roles of capsaicin-sensitive primary afferents in differential rat models of inflammatory pain: A systematic comparative study in conscious rats. Experimental Neurology. 2007;204:244–251
- . Peripheral involvement of PKA and PKC in subcutaneous bee venom-induced persistent nociception, mechanical hyperalgesia, and inflammation in rats. Pain. 2008;135:31–36
- . Pivotal involvement of neurogenic mechanism in subcutaneous bee venom induced inflammation and allodynia in unanesthetized conscious rats. Experimental Neurology. 2006;200:386–391
- . Supraspinal contribution to development of both tonic nociception and referred mirror hyperalgesia: A comparative study between formalin test and bee venom test in the rat. Anesthesiology. 2003;98:1231–1236
- . Involvement of peripheral NMDA and non-NMDA receptors in development of persistent firing of spinal wide-dynamic-range neurons induced by subcutaneous bee venom injection in the cat. Brain Res. 1999;844:98–105
- . Metabotropic receptors as targets for drugs of potential use in the treatment of neuropathic pain. J Endocrinol Invest. 2004;27:171–176
- . Pharmacology and functions of metabotropic glutamate receptors. Annu Rev Pharmacol Toxicol. 1997;37:205–237
- . Peripheral and spinal antihyperalgesic activity of SIB-1757, a metabotropic glutamate receptor (mGLUR(5)) antagonist, in experimental neuropathic pain in rats. Neurosci Lett. 2000;292:115–118
- . Behavioral evidence supporting a differential role for spinal group I and II metabotropic glutamate receptors in inflammatory hyperalgesia in sheep. Neuropharmacology. 2002;43:319–326
- . Group II metabotropic glutamate receptor activation attenuates peripheral sensitization in inflammatory states. Neuroscience. 2008;154:754–766
- . Blockade of mGluR1 receptor results in analgesia and disruption of motor and cognitive performances: Effects of A-841720, a novel non-competitive mGluR1 receptor antagonist. Br J Pharmacol. 2006;149:761–774
- . The contribution of metabotropic glutamate receptors (mGluRs) to formalin-induced nociception. Pain. 1996;68:255–263
- . Intrathecal administration of the mGluR compound, (S)-4CPG, attenuates hyperalgesia and allodynia associated with sciatic nerve constriction injury in rats. Pain. 1998;77:59–66
- . Antinociceptive effects following intrathecal pretreatment with selective metabotropic glutamate receptor compounds in a rat model of neuropathic pain. Pharmacol Biochem Behav. 2002;73:411–418
- . Glutamate receptors and nociception: Implications for the drug treatment of pain. CNS Drugs. 2001;15:29–58
- . Group III metabotropic glutamate receptors inhibit hyperalgesia in animal models of inflammation and neuropathic pain. Pain. 2008;137:112–124
- . Acute activation of the spinal cord metabotropic glutamate subtype-5 receptor leads to cold hypersensitivity in the rat. Neuropharmacology. 2003;44:423–430
- . p38 MAPK activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia. Neuron. 2002;36:57–68
- . The contribution of metabotropic glutamate receptors (mGluRs) to formalin-induced nociception. NeuroReport. 1996;7:2743–2747
- . Analgesic effects of the selective group II (mGlu2/3) metabotropic glutamate receptor agonists LY379268 and LY389795 in persistent and inflammatory pain models after acute and repeated dosing. Neuropharmacology. 2005;49:206–218
- . Central metabotropic glutamate receptors differentially participate in interleukin-1beta-induced mechanical allodynia in the orofacial area of conscious rats. J Pain. 2006;7:747–756
- . Participation of peripheral group I and II metabotropic glutamate receptors in the development or maintenance of IL-1beta-induced mechanical allodynia in the orofacial area of conscious rats. Neurosci Lett. 2006;409:173–178
- . Antinociceptive profile of a selective metabotropic glutamate receptor 1 antagonist YM-230888 in chronic pain rodent models. Eur J Pharmacol. 2007;571:8–16
- . Peripheral mGluR5 antagonist attenuated craniofacial muscle pain and inflammation but not mGluR1 antagonist in lightly anesthetized rats. Brain Res Bull. 2006;70:378–385
- . Low doses of cannabinoids enhance the antinociceptive effects of intracisternally administered mGluRs groups II and III agonists in formalin-induced TMJ nociception in rats. Pain. 2008;139:367–375
- . The peripheral role of group I metabotropic glutamate receptors on nociceptive behaviors in rats with knee joint inflammation. Neurosci Lett. 2007;416:123–127
- . Peripheral metabotropic glutamate receptor 5 mediates mechanical hypersensitivity in craniofacial muscle via protein kinase C dependent mechanisms. Neuroscience. 2007;146:375–383
- . Localization of a metabotropic glutamate receptor, mGluR7, in axon terminals of presumed nociceptive, primary afferent fibers in the superficial layers of the spinal dorsal horn: An electron microscope study in the rat. Neurosci Lett. 1997;223:153–156
- . Immunohistochemical localization of a metabotropic glutamate receptor, mGluR7, in ganglion neurons of the rat; with special reference to the presence in glutamatergic ganglion neurons. Neurosci Lett. 1996;204:9–12
- . Effects of (S)-3,4-DCPG, an mGlu8 receptor agonist, on inflammatory and neuropathic pain in mice. Neuropharmacology. 2007;52:253–262
- . The role of the vanilloid (capsaicin) receptor (TRPV1) in physiology and pathology. Eur J Pharmacol. 2004;500:351–369
- . Glutamate receptor ligands. Handb Exp Pharmacol. 2007;177:217–249
- . Groups II and III metabotropic glutamate receptors differentially modulate brief and prolonged nociception in primate STT cells. J Neurophysiol. 2000;84:2998–3009
- . Role of metabotropic glutamate receptor subtype mGluR1 in brief nociception and central sensitization of primate STT cells. J Neurophysiol. 1999;82:272–282
- . Presynaptic localization of a metabotropic glutamate receptor, mGluR7, in the primary afferent neurons: An immunohistochemical study in the rat. Neurosci Lett. 1995;202:85–88
- . Analgesic effects of mGlu1 and mGlu5 receptor antagonists in the rat formalin test. Neuropharmacology. 2006;51:623–630
- . Enhanced 3,5-dihydroxyphenylglycine-induced sustained nociceptive behaviors in rats with neuropathy or chronic inflammation. Behav Brain Res. 2007;184:150–156
- . Group II mGluR receptor agonists are effective in persistent and neuropathic pain models in rats. Pharmacol Biochem Behav. 2002;73:419–427
- . mGlu and NMDA receptor contributions to capsaicin-induced thermal and mechanical hypersensitivity. Neuropharmacology. 2005;48:325–332
- . Inflammation alters the effects of mGlu receptor agonists on spinal nociceptive neurones. Eur J Pharmaco. 1998;347:165–172
- . Structure and function of TRPV1. Pflugers Arch. 2005;451:143–150
- . mGluR5 metabotropic glutamate receptor distribution in rat and human spinal cord: A developmental study. Neuroscience Research. 1997;28:49–57
- . Metabotropic glutamate receptor involvement in models of acute and persistent pain: Prospects for the development of novel analgesics. Current Drug Targets. 2002;1:215–225
- . Metabotropic glutamate receptor subtype 5 (mGlu5) and nociceptive function. I. Selective blockade of mGlu5 receptors in models of acute, persistent and chronic pain. Neuropharmacology. 2001;40:1–9
- . mGlu5 receptors and nociceptive function II. mGlu5 receptors functionally expressed on peripheral sensory neurones mediate inflammatory hyperalgesia. Neuropharmacology. 2001;40:10–19
- . Peripheral group II metabotropic glutamate receptors (mGluR2/3) regulate prostaglandin E2-mediated sensitization of capsaicin responses and thermal nociception. J Neurosci. 2002;22:6388–6393
- . Peripheral group II metabotropic glutamate receptors mediate endogenous anti-allodynia in inflammation. Pain. 2003;106:411–417
- . Differential effects of NMDA and group I mGluR antagonists on both nociception and spinal cord protein kinase C translocation in the formalin test and a model of neuropathic pain in rats. Pain. 2001;94:17–29
- . Differential effect of peripheral glutamate (NMDA, non-NMDA) receptor antagonists on bee venom-induced spontaneous nociception and sensitization. Brain Res Bull. 2002;58:561–567
- . Behavioural and electrophysiological evidence supporting a role for group I metabotropic glutamate receptors in the mediation of nociceptive inputs to the rat spinal cord. Brain Res. 1997;777:161–169
- . Group I metabotropic glutamate receptor antagonists block secondary thermal hyperalgesia in rats with knee joint inflammation. J Pharmacol Exp Ther. 2002;300:149–156
- . Antinociceptive synergistic effect of spinal mGluR2/3 antagonist and glial cells inhibitor on peripheral inflammation-induced mechanical hypersensitivity. Brain Res Bull. 2009;79:219–223
- . Metabotropic glutamate 1alpha receptors on peripheral primary afferent fibers: Their role in nociception. Brain Res. 2001;913:18–26
- . Analgesic activity of metabotropic glutamate receptor 1 antagonists on spontaneous post-operative pain in rats. Eur J Pharmacol. 2008;580:314–321
- . Role of central and peripheral mGluR5 receptors in post-operative pain in rats. Pain. 2005;114:195–202
- . Assessing the role of metabotropic glutamate receptor 5 in multiple nociceptive modalities. Eur J Pharmacol. 2004;506:107–118
- . Ethical guidelines for investigations of experimental pain in conscious animals. Pain. 1983;16:109–110
Supported by grants from the National Natural Science Foundation of China (30471667) and Postdoctoral Science Foundation of P. R. China (2005037760; both to H.S.C.).
PII: S1526-5900(09)00664-6
doi: 10.1016/j.jpain.2009.07.013
© 2010 American Pain Society. Published by Elsevier Inc. All rights reserved.
« Previous
Next »
The Journal of Pain
Volume 11, Issue 4
, Pages 321-329
, April 2010
