The Journal of Pain
Volume 11, Issue 4 , Pages 312-320 , April 2010

Gender Differences in Risk Factors for Aberrant Prescription Opioid Use

  • Robert N. Jamison

      Affiliations

    • Pain Management Center, Departments of Anesthesia and Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts
    • Corresponding Author InformationAddress reprint requests to Dr Robert N. Jamison, Brigham and Women's Hospital, Pain Management Center, 850 Boylston Street, Chestnut Hill, MA 02467.
  • ,
  • Stephen F. Butler

      Affiliations

    • Inflexxion, Inc, Newton, Massachusetts
  • ,
  • Simon H. Budman

      Affiliations

    • Inflexxion, Inc, Newton, Massachusetts
  • ,
  • Robert R. Edwards

      Affiliations

    • Pain Management Center, Departments of Anesthesia and Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts
  • ,
  • Ajay D. Wasan

      Affiliations

    • Pain Management Center, Departments of Anesthesia and Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts

Received 15 January 2009 ,Revised 13 July 2009 ,Accepted 28 July 2009.

References 

  1. American Academy of Pain Medicine, The American Pain Society, The American Society of Addiction Medicine: Definitions related to the use of opioids for the treatment of pain: A consensus document from the American Academy of Pain Medicine, the American Pain Society, and the American Society of Addiction Medicine. ASAM, Chevy Chase, MD, 2001
  2. Arendt-Nielsen L, Bajaj P, Drewes AM. Visceral pain: Gender differences in response to experimental and clinical pain. Eur J Pain. 2004;8:465–472
  3. Ballantyne J, Mao J. Opioid therapy for chronic pain. N Engl J Med. 2003;349:1943–1953
  4. Becker WC, Sullivan LE, Tetrault JM, Desai RA, Fiellin DA. Non-medical use, abuse and dependence on prescription opioids among US adults: Psychiatric, medical, and substance use correlates. Drug Alcohol Depend. 2008;94:38–47
  5. Blanco C, Alderson D, Ogburn E, Grant B, Nunes E, Hatzenbuehler M, et al. Changes in the prevalence of non-medical prescription drug use and drug use disorders in the United States: 1991-1992 and 2001-2002. Drug Alcohol Depend. 2007;90:252–260
  6. Butler SF, Budman SH, Fernandez K, Jamison RN. Validation of a screener and opioid assessment measure for patients with chronic pain. Pain. 2004;112:65–75
  7. Butler SF, Fernandez K, Benoit C, Budman SH, Jamison RN. Validation of the revised Screener and Opioid Assessment for Patients with Pain (SOAPP-R). J Pain. 2008;9:360–372
  8. Carise D, Dugosh KL, McLellan AT, Camilleri A, Woody GE, Lynch KG. Prescription OxyContin abuse among patients entering addiction treatment. Am J Psychiatry. 2007;164:1750–1756
  9. Chabal C, Erjavec MK, Jacobson L, Mariano A, Chaney E. Prescription opiate abuse in chronic pain patients: Clinical criteria, incidence, and predictors. Clin J Pain. 1997;13:150–155
  10. Cleeland CS, Ryan KM. Pain assessment: Global use of the Brief Pain Inventory. Ann Acad Med Singapore. 1994;23:129–138
  11. Compton PJ, Darakjian J, Miotto K. Screening for addiction in patients with chronic pain and “problematic” substance use: Evaluation of a pilot assessment tool. J Pain Sympt Manage. 1998;16:355–363
  12. Crowne DP, Marlowe D. The Approval Motive: Studies in Evaluative Dependence. New York: Wiley; 1964;
  13. Eriksen J, Jensen MK, Sjogren P, Ekholm O, Rasmussen NK. Epidemiology of chronic nonmalignant pain in Denmark. Pain. 2003;106:221–228
  14. Fishbain DA, Rosomoff HL, Rosomoff RS. Drug abuse, dependence, and addiction in chronic pain patients. Clin J Pain. 1992;8:77–85
  15. Fleming M, Balousek S, Klessig C, Mundt M, Brown D. Substance use disorders in a primary care sample receiving daily opioid therapy. J Pain. 2007;9:573–582
  16. Greenspan J, Craft R, LeResche L, Arendt-Nielsen L, Berkley K, Fillingim R, et al. Studying sex and gender differences in pain and analgesia: A consensus report. Pain. 2007;132:S26–S45
  17. Hojsted J, Sjogen P. Addiction to opioids in chronic pain patients: A literature review. Eur J Pain. 2007;11:490–518
  18. Joransson DE, Ryan KM, Gilson AM, Dahl JL. Trends in medical use and abuse of opioid analgesics. JAMA. 2000;283:1710–1714
  19. Katon W, Egan K, Miller D. Chronic pain: Lifetime psychiatric diagnosis and family history. Am J Psych. 1985;142:1156–1160
  20. Kelly JP, Cook SF, Kaufman DW, Anderson T, Rosenberg L, Mitchell AA. Prevalence and characteristics of opioid use in the US adult population. Pain. 2008;138:507–513
  21. Kessler RC, Berglund P, Demler O, Jin R, Merikangas KR, Walters EE. Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry. 2005;62:593–602
  22. Mackenzie CS, Gekoski WL, Knox VJ. Age, gender, and the underutilization of mental health services: The influence of help-seeking attitudes. Aging Ment Health. 2006;10:574–582
  23. Manchikanti L, Giordano J, Boswell MV, Fellows B, Manchukonda R, Pampati V. Psychological factors as predictors of opioid abuse and illicit drug use in chronic pain patients. J Opioid Manag. 2007;3:89–100
  24. McCabe SE, Teter CJ, Boyd CJ. Illicit use of prescription pain medication among college students. Drug Alcohol Depend. 2005;77:37–47
  25. Michna E, Jamison RN, Pham LD, Ross JD, Janfaza D, Nedeljkovic SS, et al. Urine toxicology screening among chronic pain patients on opioid therapy: Frequency and predictability of abnormal findings. Clin J Pain. 2007;23:173–179
  26. Michna E, Ross EL, Hynes WL, Nedeljkovic SS, Soumekh S, Janfaza D, et al. Predicting aberrant drug behavior in patients treated for chronic pain: Importance of abuse history. J Pain Symptom Manage. 2004;28:250–258
  27. Nedeljkovic SS, Wasan AD, Jamison RN. Assessment of efficacy of long-term opioid therapy in pain patients with substance abuse potential. Clin J Pain. 2002;18:S39–S51
  28. Office of Applied Studies: Overview of findings from the 2002 National Survey on Drug Use and Health. Rockville, MD, Substance Abuse and Mental Health Services Administration, 2003
  29. Portenoy RK, Foley KM. Chronic use of opioid analgesics in non-malignant pain: Report of 38 cases. Pain. 1986;25:171–186
  30. Reynolds WM. Development of reliable and valid short forms of the Marlowe-Crowne Social Desirability Scale. J Clin Psychol. 1982;38:119–125
  31. Rosenblum A, Parrino M, Schnoll SH, Fong C, Maxwell C, Cleeland CM, et al. Prescription opioid abuse among enrollees into methadone maintenance treatment. Drug Alcohol Depend. 2007;90:64–71
  32. Russell MB, Kristiansen HA, Saltyte-Benth J, Kvaerner KJ. A cross-sectional population-based survey of migraine and headache in 21,177 Norwegians: The Akershus sleep apnea project. J Headache Pain. 2008;9:339–347
  33. Savage SR. Assessment for addiction in pain-treatment settings. Clin J Pain. 2002;18:S28–S38
  34. Simoni-Wastila L, Ritter G, Strickler G. Gender and other factors associated with the nonmedical use of abusable prescription drugs. Substance Use Misuse. 2004;39:1–23
  35. Stinson FS, Grant BF, Dawson DA, Ruan WJ, Huang B, Saha T. Comorbidity between DSM-IV alcohol and specific drug use disorders in the United States: Results from the National Epidemiologic Survey on Alcohol and Related Conditions. Drug Alcohol Depend. 2005;80:105–116
  36. Sullivan MD, Edlund MJ, Steffick D, Unutzer J. Regular use of prescribed opioids: Association with common psychiatric disorders. Pain. 2005;119:95–103
  37. Tan G, Jensen MP, Thornby JI, Shanti BF. Validation of the Brief Pain Inventory for Nonmalignant Pain. J Pain. 2004;5:133–137
  38. Tempelhof TC, Allen JS. Partner-specific investment strategies: Similarities and differences in couples and associations with sociosexual orientation and attachment dimensions. Person Individ Diff. 2008;45:41–48
  39. Tetrault JM, Desai RA, Becker WC, Fiellin DA, Concato J, Sullivan LE. Gender and non-medical use of prescription opioids: Results from a national US survey. Addiction. 2007;103:258–268
  40. Tsang A, Von Korff M, Lee S, Alonso J, Karam E, Angermeyer MC, et al. Common chronic pain conditions in developed and developing countries: Gender and age differences and comorbidity with depression-anxiety disorders. J Pain. 2008;9:883–891
  41. Turk DC, Swanson KS, Gatchel RJ. Predicting opioid misuse by chronic pain patients: A systematic review and literature synthesis. Clin J Pain. 2008;24:497–508
  42. Walitzer KS, Dearing RL. Gender differences in alcohol and substance use relapse. Clin Psychol Rev. 2006;26:128–148
  43. Wasan AD, Butler SF, Budman SH, Benoit C, Fernandez K, Jamison RN. Psychiatric history and psychological adjustment as risk factors for aberrant drug-related behavior among patients with chronic pain. Clin J Pain. 2007;23:307–315
  44. Wasan AD, Correll DJ, Kissin I, O'Shea S, Jamison RN. Iatrogenic addiction in patients treated for acute or subacute pain: A systematic review. J Opioid Manage. 2006;2:16–22
  45. Wasan AD, Wootton J, Jamison RN. Dealing with difficult patients in your pain practice. Reg Anesth Pain Med. 2005;30:184–192
  46. Weaver M, Schnoll S. Abuse liability in opioid therapy for pain treatment in patients with an addiction history. Clin J Pain. 2002;18:61–69
  47. Webster LR, Dove B. Avoiding Opioid Abuse While Managing Pain: A Guide for Practitioners. North Branch, MN: Sunrise River Press; 2007;
  48. Webster LR, Webster RM. Predicting aberrant behaviors in opioid-treated patients: Preliminary validation of the Opioid Risk Tool. Pain Med. 2005;6:432–442
  49. Zahn-Waxler C, Shirtcliff EA, Marceau K. Disorders of childhood and adolescence: Gender and psychopathology. Annu Rev Clin Psychol. 2008;4:275–303

 Supported in part by grants (DA015617, Dr Butler; K23 DA020681, Dr Wasan; and R21 DA024298, Dr Jamison) from the National Institute on Drug Abuse, from the National Institutes of Health, Bethesda, Maryland, and the Arthritis Foundation (Investigator Award, Dr Wasan).

PII: S1526-5900(09)00690-7

doi: 10.1016/j.jpain.2009.07.016

The Journal of Pain
Volume 11, Issue 4 , Pages 312-320 , April 2010