The Journal of Pain
Volume 11, Issue 4 , Pages 378-387, April 2010

Activation of NMDA Receptors in the Brainstem, Rostral Ventromedial Medulla, and Nucleus Reticularis Gigantocellularis Mediates Mechanical Hyperalgesia Produced by Repeated Intramuscular Injections of Acidic Saline in Rats

  • Luis F. Da Silva

      Affiliations

    • Graduate Program in Physical Therapy and Rehabilitation Sciences, Neuroscience Graduate Program, Pain Research Program, The University of Iowa, Iowa City
    • ,
  • Josimari M. DeSantana

      Affiliations

    • Department of Physical Therapy, Federal University of Sergipe, Aracajú, Sergipe, Brazil
    • ,
  • Kathleen A. Sluka

      Affiliations

    • Graduate Program in Physical Therapy and Rehabilitation Sciences, Neuroscience Graduate Program, Pain Research Program, The University of Iowa, Iowa City
    • Corresponding Author InformationAddress reprint requests to Dr Kathleen A. Sluka, Physical Therapy and Rehabilitation Science, 1-252 Medical Education Building, The University of Iowa, Iowa City, IA 52242-1190.

Received 10 April 2009; received in revised form 23 July 2009; accepted 15 August 2009. published online 23 October 2009.

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 Supported by grants NIH R01 AR052316.

 The authors have no conflict of interest in the work presented.

 Drs Da Silva and DeSantana contributed equally to this work.

PII: S1526-5900(09)00695-6

doi:10.1016/j.jpain.2009.08.006

The Journal of Pain
Volume 11, Issue 4 , Pages 378-387, April 2010

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