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The Journal of Pain
Volume 11, Issue 6
, Pages 588-599
, June 2010
Spinal Nerve Ligation in Mouse Upregulates TRPV1 Heat Function in Injured IB4-Positive Nociceptors
References
- . Glial cell-line-derived neurotrophic factor expression in skin alters the mechanical sensitivity of cutaneous nociceptors. J Neurosci. 2006;26:2981–2990
- . NGF and GDNF differentially regulate TRPV1 expression that contributes to development of inflammatory thermal hyperalgesia. Eur J Neurosci. 2004;20:2303–2310
- . A distinct subgroup of small DRG cells express GDNF receptor components and GDNF is protective for these neurons after nerve injury. J Neurosci. 1998;18:3059–3072
- . Morphological evidence for functional capsaicin receptor expression and calcitonin gene-related peptide exocytosis in isolated peripheral nerve axons of the mouse. Neuroscience. 2004;126:585–590
- . Parallel “pain” pathways arise from subpopulations of primary afferent nociceptor. Neuron. 2005;47:787–793
- . Peripheral inflammation selectively increases TRPV1 function in IB4-positive sensory neurons from adult mouse. Pain. 2005;115:37–49
- . Mechanisms of neuropathic pain. Neuron. 2006;52:77–92
- . Impaired nociception and pain sensation in mice lacking the capsaicin receptor. Science. 2000;288:306–313
- . The capsaicin receptor: A heat-activated ion channel in the pain pathway. Nature. 1997;389:816–824
- . A capsaicin-receptor homologue with a high threshold for noxious heat. Nature. 1999;398:436–441
- . Thermosensitive TRPV channel subunits coassemble into heteromeric channels with intermediate conductance and gating properties. J Gen Physiol. 2007;129:191–207
- . Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia. Nature. 2000;405:183–187
- . Differential response properties of IB(4)-positive and -negative unmyelinated sensory neurons to protons and capsaicin. J Neurophysiol. 2003;89:513–524
- . Improved superfusion technique for rapid cooling or heating of cultured cells under patch-clamp conditions. J Neurosci Methods. 2006;151:178–185
- . Spontaneous pain, both neuropathic and inflammatory, is related to frequency of spontaneous firing in intact C-fiber nociceptors. J Neurosci. 2006;26:1281–1292
- . A-425619 [1-isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a novel and selective transient receptor potential type V1 receptor antagonist, blocks channel activation by vanilloids, heat, and acid. J Pharmacol Exp Ther. 2005;314:400–409
- . Electrophysiological differences between nociceptive and non-nociceptive dorsal root ganglion neurones in the rat in vivo. J Physiol. 2005;565:927–943
- . VR1, but not P2X(3), increases in the spared L4 DRG in rats with L5 spinal nerve ligation. Pain. 2002;99:111–120
- . Heat-evoked activation of the ion channel, TRPV4. J Neurosci. 2002;22:6408–6414
- . GDNF mRNA in Schwann cells and DRG satellite cells after chronic sciatic nerve injury. Neuroreport. 1996;7:857–860
- . Effects of spinal nerve ligation on immunohistochemically identified neurons in the L4 and L5 dorsal root ganglia of the rat. J Comp Neurol. 2004;475:575–589
- . A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain. 1988;32:77–88
- . Homo- and heteromeric assembly of TRPV channel subunits. J Cell Sci. 2005;118:917–928
- . A-425619 [1-isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a novel transient receptor potential type V1 receptor antagonist, relieves pathophysiological pain associated with inflammation and tissue injury in rats. J Pharmacol Exp Ther. 2005;314:410–421
- . VR1 protein expression increases in undamaged DRG neurons after partial nerve injury. Eur J Neurosci. 2001;13:2105–2114
- . Direct activation of capsaicin receptors by products of lipoxygenases: Endogenous capsaicin-like substances. Proc Natl Acad Sci USA. 2000;97:6155–6160
- . An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat. Pain. 1992;50:355–363
- . Properties of somata of spinal dorsal root ganglion cells differ according to peripheral receptor innervated. J Neurophysiol. 1988;60:1584–1596
- . Acutely dissociated sensory neurons: normal or neuropathic? Focus on: “Dissociation of dorsal root ganglion neurons induces hyperexcitability that is maintained by increased responsiveness to cAMP and cGMP.”. J Neurophysiol. 2007;97:1–2
- . TRPV1 unlike TRPV2 is restricted to a subset of mechanically insensitive cutaneous nociceptors responding to heat. J Pain. 2008;9:298–308
- . TRPV channels as thermosensory receptors in epithelial cells. Pflugers Arch. 2005;451:160–167
- . Pericellular Griffonia simplicifolia I isolectin B4-binding ring structures in the dorsal root ganglia following peripheral nerve injury in rats. J Comp Neurol. 2001;439:259–274
- . Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor. Cell. 2000;103:525–535
- . Tactile allodynia in the absence of C-fiber activation: Altered firing properties of DRG neurons following spinal nerve injury. Pain. 2000;85:503–521
- . Small primary sensory neurons innervating epidermis and viscera display differential phenotype in the adult rat. Neurosci Res. 2001;41:355–363
- . The effects of excessive heat on heat-activated membrane currents in cultured dorsal root ganglia neurons from neonatal rat. Pain. 2002;95:207–214
- . Similar electrophysiological changes in axotomized and neighboring intact dorsal root ganglion neurons. J Neurophysiol. 2003;89:1588–1602
- . Chronic post-surgical pain: 10 years on. Br J Anaesth. 2008;101:77–86
- . Chronic pain after surgery. Br J Anaesth. 2001;87:88–98
- . TRPV3 in keratinocytes transmits temperature information to sensory neurons via ATP. Pflugers Arch. 2009;458:1093–1102
- . Differential expression of the mRNA for the vanilloid receptor subtype 1 in cells of the adult rat dorsal root and nodose ganglia and its downregulation by axotomy. J Neurosci. 1999;19:1844–1854
- . Immune and inflammatory mechanisms in neuropathic pain. Brain Res Rev. 2006;51:240–264
- . IB4-binding DRG neurons switch from NGF to GDNF dependence in early postnatal life. Neuron. 1997;19:849–861
- . Activation of central terminal vanilloid receptor-1 receptors and alpha beta-methylene-ATP-sensitive P2X receptors reveals a converged synaptic activity onto the deep dorsal horn neurons of the spinal cord. J Neurosci. 2002;22:1228–1237
- . Differential regulation of mRNAs for GDNF and its receptors Ret and GDNFR alpha after sciatic nerve lesion in the mouse. Eur J Neurosci. 1997;9:1450–1460
- . Enhancement by prostaglandin E2 of bradykinin activation of embryonic rat sensory neurones. J Physiol. 1994;480:485–492
- . A heat-sensitive TRP channel expressed in keratinocytes. Science. 2002;296:2046–2049
- . N-(4-Tertiarybutylphenyl)-4-(3-cholorphyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a novel, orally effective vanilloid receptor 1 antagonist with analgesic properties, II: In vivo characterization in rat models of inflammatory and neuropathic pain. J Pharmacol Exp Ther. 2003;306:387–393
- . Novel expression of vanilloid receptor 1 on capsaicin-insensitive fibers accounts for the analgesic effect of capsaicin cream in neuropathic pain. J Pharmacol Exp Ther. 2003;304:940–948
- . Species and strain differences in rodent sciatic nerve anatomy: Implications for studies of neuropathic pain. Pain. 2008;136:188–201
- . Somal membrane properties of physiologically identified sensory neurons in the rat: Effects of nerve growth factor. J Neurophysiol. 1992;68:2033–2041
- . Potentiation of glutamatergic synaptic transmission by protein kinase C-mediated sensitization of TRPV1 at the first sensory synapse. J Physiol. 2007;581:631–647
- . TRPV3 is a temperature-sensitive vanilloid receptor-like protein. Nature. 2002;418:186–190
- . Isolectin B(4)-positive and -negative nociceptors are functionally distinct. J Neurosci. 1999;19:6497–6505
- . Leukaemia inhibitory factor is required for normal inflammatory responses to injury in the peripheral and central nervous systems in vivo and is chemotactic for macrophages in vitro. Eur J Neurosci. 2000;12:457–466
- . Bradykinin lowers the threshold temperature for heat activation of vanilloid receptor 1. J Neurophysiol. 2002;88:544–548
- . Key role of the dorsal root ganglion in neuropathic tactile hypersensibility. Eur J Pain. 2004;8:135–143
- . Sensory neurons of the rat sciatic nerve. Exp Neurol. 1991;114:82–103
- . The cloned capsaicin receptor integrates multiple pain-producing stimuli. Neuron. 1998;21:531–543
- . Cytotoxic targeting of isolectin IB4-binding sensory neurons. Neuroscience. 2001;108:143–155
- . Wall and Melzack's Textbook of Pain. 5th ed.. Philadelphia, PA: Elsevier; 2006;pp 905-927
- . An alternative splicing product of the murine trpv1 gene dominant negatively modulates the activity of TRPV1 channels. J Biol Chem. 2004;279:37423–37430
- . Nociceptors lacking TRPV1 and TRPV2 have normal heat responses. J Neurosci. 2004;24:6410–6415
- . Early onset of spontaneous activity in uninjured C-fiber nociceptors after injury to neighboring nerve fibers. J Neurosci. 2001;21:RC140
- . Dissociation of dorsal root ganglion neurons induces hyperexcitability that is maintained by increased responsiveness to cAMP and cGMP. J Neurophysiol. 2007;97:15–25
- . The TRPV1/2/3 activator 2-aminoethoxydiphenyl borate sensitizes native nociceptive neurons to heat in wildtype but not TRPV1 deficient mice. Neuroscience. 2005;135:1277–1284
- . Glial cell line-derived neurotrophic factor is a survival factor for isolectin B4-positive, but not vanilloid receptor 1-positive, neurons in the mouse. J Neurosci. 2002;22:4057–4065
- . Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide. Nature. 1999;400:452–457
- . Topographically distinct epidermal nociceptive circuits revealed by axonal tracers targeted to Mrgprd. Neuron. 2005;45:17–25
Supported by NIH grant NS40538 (to C.L.S.).
PII: S1526-5900(09)00773-1
doi: 10.1016/j.jpain.2009.09.018
© 2010 American Pain Society. Published by Elsevier Inc. All rights reserved.
« Previous
The Journal of Pain
Volume 11, Issue 6
, Pages 588-599
, June 2010
