The Journal of Pain
Volume 12, Issue 1 , Pages 94-100, January 2011

A Tropomyosine Receptor Kinase Inhibitor Blocks Spinal Neuroplasticity Essential for the Anti-Hypersensitivity Effects of Gabapentin and Clonidine in Rats With Peripheral Nerve Injury

  • Ken-ichiro Hayashida
  • ,
  • James C. Eisenach

      Affiliations

    • Corresponding Author InformationAddress reprint requests to James C. Eisenach, MD, Department of Anesthesiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1009.

Department of Anesthesiology, Wake Forest University School of Medicine, Winston-Salem, North Carolina

Received 14 March 2010; received in revised form 16 April 2010; accepted 13 May 2010. published online 20 July 2010.

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 Supported by grants NS57594 to J.E. and DA27690 to K.H. from the National Institute of Health, Bethesda, Maryland.

PII: S1526-5900(10)00534-1

doi:10.1016/j.jpain.2010.05.005

The Journal of Pain
Volume 12, Issue 1 , Pages 94-100, January 2011