Abstract
Although most cases of temporomandibular muscle and joint disorders (TMJD) are mild
and self-limiting, about 10% of TMJD patients develop severe disorders associated
with chronic pain and disability. It has been suggested that fibromyalgia and widespread
pain play a significant role in TMJD chronicity. This paper assessed the effects of
fibromyalgia and widespread pain on clinically significant TMJD pain (GCPS II-IV).
Four hundred eighty-five participants recruited from the Minneapolis/St. Paul area
through media advertisements and local dentists received examinations and completed
the Graded Chronic Pain Scale (GCPS) at baseline and at 18 months. Baseline widespread
pain (OR: 2.53, P = .04) and depression (OR: 5.30, P = .005) were associated with onset of clinically significant pain (GCPS II-IV) within
18 months after baseline. The risk associated with baseline fibromyalgia was moderate,
but not significant (OR: 2.74, P = .09). Persistence of clinically significant pain was related to fibromyalgia (OR:
2.48, P = .02) and depression (OR: 2.48, P = .02). These results indicate that these centrally generated pain conditions play
a role in the onset and persistence of clinically significant TMJD.
Perspective
Fibromyalgia and widespread pain should receive important consideration when evaluating
and developing a treatment plan for patients with TMJD.
Key words
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to The Journal of PainAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Comparison of Beck Depression Inventories -IA and -II in psychiatric outpatients.J pers assess. 1996; 67: 588-597
- Fibromyalgia, chronic fatigue syndrome, and myofascial pain syndrome.Curr Opin Rheumatol. 2001; 13: 117-127
- Comparison of clinical and psychologic features of fibromyalgia and masticatory myofascial pain.J Orofac Pain. 1998; 12: 35-41
- The relationship between “stress” and pain: Lessons learned from fibromyalgia and related conditions.in: Castro-Lopes José Current Topics in Pain - 12th World Congress on Pain. IASP, Seattle, WA2009: 245-270
- Temporomandibular disorders pain.in: Crombie I.K. Croft P.R. Linton S.J. LeResche L. Von Korff M. Epidemiology of Pain. IASP, Seattle, WA1999: 203-233
- Research diagnostic criteria for temporomandibular disorders: Review criteria, examinations and specifications, critique.J Craniomandib Disord. 1992; 6: 301-355
- Sex, gender, and pain: Women and men really are different.Curr Rev Pain. 2000; 4: 24-30
- Sex, gender, and pain: A review of recent clinical and experimental findings.J Pain. 2009; 10: 447-485
- General musculoskeletal complaints in a group of patients with craniomandibular disorders (CMD). A case control study.Swed Dent J. 1991; 15: 179-185
- Presence of orofacial pain and temporomandibular disorder in fibromyalgia. A study by questionnaire.Swed Dent J. 1999; 23: 185-192
- Evidence of dysfunctional pain inhibition in fibromyalgia reflected in rACC during provoked pain.Pain. 2009; 144: 95-100
- Widespread pain as a risk factor for dysfunctional temporomandibular disorder pain.Pain. 2003; 102: 257-263
- The pain of fibromyalgia syndrome is due to muscle hypoperfusion induced by regional vasomotor dysregulation.Med Hypotheses. 2007; 69: 517-525
- The relationship between temporomandibular disorders and stress-associated syndromes.Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1998; 86: 416-420
- Accelerated brain gray matter loss in fibromyalgia patients: premature aging of the brain?.J Neurosci. 2007; 27: 4004-4007
- Epidemiology of temporomandibular disorders: Implications for the investigation of etiologic factors.Crit Rev Oral Biol Med. 1997; 8: 291-305
- Predictors of onset of facial pain and temporomandibular disorders in early adolescence.Pain. 2007; 129: 269-278
- Sensitivity of patients with painful temporomandibular disorders to experimentally evoked pain: Evidence for altered temporal summation of pain.Pain. 1998; 76: 71-81
- Chronic pain conditions in women.J Womens Health. 1999; 8: 313-320
- Interexaminer reliability and clinical validity of the temporomandibular index: A new outcome measure for temporomandibular disorders.J Orofac Pain. 2002; 16: 296-304
- The incidence of pain in the muscles of mastication in patients with fibromyalgia.J Mass Dent Soc. 1998; 47: 8-12
- The relationship between fibromyalgia and temporomandibular disorders: Prevalence and symptom severity.J Rheumatol. 1996; 23: 1948-1952
- Enhanced temporal summation of second pain and its central modulation in fibromyalgia patients.Pain. 2002; 99: 49-59
- Longitudinal outcome of temporomandibular disorders: A 5-year epidemiologic study of muscle disorders defined by research diagnostic criteria for temporomandibular disorders.J Orofac Pain. 2003; 17: 9-20
- Myofascial face pain. Clinical characteristics of those with regional vs. widespread pain.J Am Dent Assoc. 2000; 131: 161-171
- Oral symptoms associated with fibromyalgia syndrome.J Rheumatol. 2003; 30: 1841-1845
- Differential treatment responses of TMD patients as a function of psychological characteristics.Pain. 1995; 61: 103-112
- The prevalence and treatment needs of subjects with temporomandibular disorders.J Am Dent Assoc. 1990; 120: 295-303
- Pain maps from facial pain patients indicate a broad pain geography.J Dent Res. 1998; 77: 1465-1472
- An epidemiologic comparison of pain complaints.Pain. 1988; 32: 173-183
- Grading the severity of chronic pain.Pain. 1992; 50: 133-149
- First onset of common pain symptoms: A prospective study of depression as a risk factor.Pain. 1993; 55: 251-258
- Functional somatic syndromes: One or many?.Lancet. 1999; 354: 936-939
- The American College of Rheumatology 1990 criteria for the classification of fibromyalgia. Report of the Multicenter Criteria Committee.Arthritis Rheum. 1990; 33: 160-172
Article info
Publication history
Published online: May 13, 2010
Accepted:
February 12,
2010
Received in revised form:
January 31,
2010
Received:
September 22,
2009
Footnotes
This study was funded by NIH/NIDCR grant R01DE11252 and the University of Minnesota Oral Health Research Center (NIH/NIDCR grant DE09737-09). This project was also supported by the National Institute of Dental and Craniofacial Research's TMJ Implant Registry and Repository (NIH/NIDCR Contract # N01-De-22635).
Identification
Copyright
© 2010 American Pain Society. Published by Elsevier Inc. All rights reserved.