The recently published article by Cepeda et al compiling pain trial data from the
ClinicalTrials.gov database is important for the large number of randomized trials summarized (>7,000
trials).
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Much of the analysis focuses on attrition. However, several issues arising from the
analyses warrant comment.To read this article in full you will need to make a payment
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References
- Use of ClinicalTrials.gov to estimate condition-specific nocebo effects and other factors affecting outcomes of analgesic trials.J Pain. 2013; 14: 405-411
- Enriched enrolment with randomized withdrawal (EERW): Time for a new look at clinical trial design in chronic pain.Pain. 2008; 135: 217-220
- Two-stage enriched enrolment pain trials: A brief review of designs and opportunities for broader application.Pain. 2010; 148: 8-13
- Placebo response in neuropathic pain trials.Pain. 2008; 138: 479-483
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© 2013 American Pain Society. Published by Elsevier Inc. All rights reserved.
