- •We studied the link between sleep and experimental pain in knee osteoarthritis.
- •Sleep disruption was related to altered pain processing by sex and ethnicity/race.
- •Disrupted sleep was related to greater heat and pressure pain facilitation in women.
- •Compared to African Americans, whites with poor sleep had less pain inhibition.
- •Whites with poor sleep had lower pressure pain thresholds than African Americans.
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Support provided by the National Institutes of Health/National Institute on Aging (grant number R01AG033906) and the University of Florida Clinical and Translational Science Institute (grant number UL1TR000064, R.B.F., primary investigator), and the University of Alabama at Birmingham Clinical and Translational Science Institute (grant number UL1TR000165).
M.E.P. received support from the Agency for Healthcare Research and Quality (5 T32 HS013852-09) and the National Institute on Minority Health and Health Disparities (3 P60 MD000502-08S1). T.L.G. received support from the John A. Hartford Foundation (2011-2013) as a Building Academic Geriatric Nursing Capacity Scholar and a Mayday Fund grantee (grant number AAN 11-116). K.T.S. received support from the National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases (K23AR062099). E.J.B. is supported by a National Institute of Neurological Disorders and Stroke training grant T32NS045551 to the University of Florida Pain Research and Intervention Center of Excellence.
The authors have no conflicts of interest to declare.
Supplementary data accompanying this article are available online at www.jpain.org and www.sciencedirect.com.