- •Having no or few pain sites may not differ in its risk factors compared with multiple pain.
- •Anxiety, depression, insomnia, and obesity are key predictors of increasing pain sites.
- •Associations of lifestyle factors attenuated in the within-subject analysis.
- •We found a substantial stability of number of pain sites within individuals over time.
- •Our study adds valued input to the ongoing debate regarding the course of multisite pain.
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The authors have no conflicts of interest to declare.