- •Screening tests are an important risk evaluation tool for aberrant opioid use.
- •Screeners also have the potential to be misused in clinical decision-making.
- •Proper interpretation recognizes that sensitivity does not imply predictive value.
- •The variation in base rates for aberrant opioid use complicates predictive validity.
- •With low base rates, positive results on screeners must be interpreted with caution.
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This work was partially supported by a grant from the National Center for Complementary and Integrative Health (R34AT008398).
The authors have no conflicts of interest to declare.