As a statistician who is interested in methods of meta-analysis, the letter by Gatchel
and Licciardone
3
prompted me to examine the article by O'Keeffe et al
10
on comparative effectiveness of conservative interventions for nonspecific chronic
spinal pain. I was discouraged to find numerous shortcomings in methods, analysis,
and reporting that undermine its validity.- O'Keeffe M.
- Purtill H.
- Kennedy N.
- Conneely M.
- Hurley J.
- O'Sullivan P.
- Dankaerts W.
- O'Sullivan K.
Comparative effectiveness of conservative interventions for nonspecific chronic spinal
pain: Physical, behavioral/psychologically informed, or combined? A systematic review
and meta-analysis.
J Pain. 2016; 17: 755-774
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The author has no conflicts of interest to declare.
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© 2017 by the American Pain Society
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- Criticism for Following Recommended PracticeThe Journal of PainVol. 19Issue 2
- PreviewThe author David C. Hoaglin criticises the methods used in our review. Specifically, he questions using a random effects model, halving of sample sizes to avoid double counting of participants, and assessing heterogeneity using the I2 statistic. However, we were in line with the recommendations of the Cochrane Back Review Group1 in using these approaches—of which the author is either unaware, or does not acknowledge. This is compounded by the fact that the author provides no evidence-based, rigorously tested alternative for these choices (eg, using the I2 statistic).
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