Abstract
Persistent Post-Mastectomy Pain (PPMP) is a common condition that can follow surgeries
for breast cancer, the most common cancer in women. Because of the frequency of PPMP
and its potential severity, it has received increasing research attention. This manuscript
reviews the recent research literature, beginning with a brief history and then relevant
medical, surgical, demographic, and psychosocial risk factors. Subsequently, social,
psychological, and functional sequelae that have been linked to PPMPS are considered,
as is research on current pharmacological, psychological, and rehabilitative approaches
to treatment. The review concludes with a discussion of directions for future research
and treatment that might reduce the incidence and impact of PPMP on breast cancer
survivors.
Perspective
This article describes current research literature involving mechanisms, risks, and
treatments related to persistent post-mastectomy pain. Implications of research findings
also are discussed for pre- and post-surgical approaches to pain management, current
treatments, and promising research directions.
Keywords
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Article info
Publication history
Published online: July 02, 2018
Footnotes
Disclosures:
Funding: This work was supported by the National Institutes of Health to Southern Illinois University – Edwardsville (Contract No. HHSN271201500056C).
Conflicts of Interest: The authors have no financial conflicts of interest related to the content of this paper.
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