Abstract
Patients undergoing thoracic surgery experience particular challenges for acute pain
management. Availability of standardized diagnostic criteria for identification of
acute pain after thoracotomy and video assisted thoracic surgery (VATS) would provide
a foundation for evidence-based management and facilitate future research. The Analgesic,
Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities,
and Networks (ACTTION) public-private partnership with the United States Food and
Drug Administration, the American Pain Society (APS), and the American Academy of
Pain Medicine (AAPM) formed the ACTTION-APS-AAPM Pain Taxonomy (AAAPT) initiative
to address absence of acute pain diagnostic criteria. A multidisciplinary working
group of pain experts was invited to develop diagnostic criteria for acute thoracotomy
and VATS pain. The working group used available studies and expert opinion to characterize
acute pain after thoracotomy and VATS using the 5-dimension taxonomical structure
proposed by AAAPT (i.e., core diagnostic criteria, common features, modulating factors,
impact/functional consequences, and putative mechanisms). The resulting diagnostic
criteria will serve as the starting point for subsequent empirically validated criteria.
Perspective Item
This article characterizes acute pain after thoracotomy and VATS using the 5-dimension
taxonomical structure proposed by AAAPT (ie, core diagnostic criteria, common features,
modulating factors, impact and/or functional consequences, and putative mechanisms).
Key Words
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to The Journal of PainAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Single versus multi-incisional video-assisted thoracic surgery: A systematic review and meta-analysis.J Laparoendosc Adv Surg Tech A. 2017; 28: 174-185
- Intercostal muscle flap for decreasing pain after thoracotomy: a prospective randomized trial.Ann Thorac Surg. 2010; 89: 195-199
- Local anaesthetics and regional anaesthesia for preventing chronic pain after surgery.Cochrane Database Syst Rev. 2012; 10CD007105
- Regional anaesthesia to prevent chronic pain after surgery: A Cochrane systematic review and meta-analysis.Br J Anaesth. 2013; 111: 711-720
- Sex- and age-related differences in morphine requirements for postoperative pain relief.Anesthesiology. 2005; 103: 156-160
- Intensity, latency and duration of post-thoracotomy pain: relationship to personality traits.Funct Neurol. 1990; 5: 321-332
- Analgesic efficacy and safety of thoracic paravertebral and epidural analgesia for thoracic surgery: A systematic review and meta-analysis.Interact Cardiovasc Thorac Surg. 2014; 18: 626-635
- The comparative effects of postoperative analgesic therapies on pulmonary outcome: cumulative meta-analyses of randomized, controlled trials.Anesth Analg. 1998; 86: 598-612
- Lung function after lobectomy: a randomized, double-blinded trial comparing thoracic epidural ropivacaine/sufentanil and intravenous morphine for patient-controlled analgesia.Anesth Analg. 2007; 105: 238-244
- Incidence and severity of chronic pain at 3 and 6 months after thoracotomy: Meta-analysis.The j pain: off j Am Pain Soc. 2014; 15: 887-897
- Pain-related limitations in daily activities following thoracic surgery in a United States Population.Pain Physician. 2017; 20: E367-E378
- AAAPT: Assessment of the acute pain trajectory.Pain Med. 2021; 22: 533-547
- Preoperative patient expectations of postoperative pain are associated with moderate to severe acute pain after VATS.Pain Med. 2018; 20: 543-554
- A prospective study of chronic pain after thoracic surgery.Anesthesiology. 2017; 126: 938-951
- Postoperative pain and quality of life after lobectomy via video-assisted thoracoscopic surgery or anterolateral thoracotomy for early stage lung cancer: A randomised controlled trial.The Lancet. Oncology. 2016; 17: 836-844
- Neurophysiologic assessment of nerve impairment in posterolateral and muscle-sparing thoracotomy.J Thorac Cardiovasc Surg. 1998; 115: 841-847
- Evaluation of respiratory muscle strength by randomized controlled trial comparing thoracoscopy, transaxillary thoracotomy, and posterolateral thoracotomy for lung biopsy.Eur J Cardiothorac Surg. 2006; 29: 596-600
- Opioid use trajectories after thoracic surgery among veterans in the United States.Eur J Pain. 2020; 24: 1569-1584
- High-dose methylprednisolone in video-assisted thoracoscopic surgery lobectomy: a randomized controlled trial.Eur J Cardiothorac Surg. 2018; 53: 209-215
- Analysis of unexpected conversion to thoracotomy during thoracoscopic lobectomy in lung cancer.Ann Thorac Surg. 2015; 100: 968-973
- A prospective, double-blinded, randomized trial evaluating the use of preemptive analgesia of the skin before thoracotomy.Ann Thorac Surg. 2003; 76: 1055-1058
- Intercostal muscle flap reduces the pain of thoracotomy: A prospective randomized trial.J Thorac Cardiovasc Surg. 2005; 130: 987-993
- Intracostal sutures decrease the pain of thoracotomy.Ann Thorac Surg. 2003; 76 (discussion 411-402): 407-411
- The transition of acute postoperative pain to chronic pain: An integrative overview of research on mechanisms.The J pain: off J Am Pain Soc. 2017; 18 (Available online at): 359.e1-359.e38
- The epidemiology and risk factors for postoperative pneumonia.J Clin Med Res. 2017; 9: 466-475
- The effect of pre-emptive intravenous Dexketoprofen + thoracal epidural analgesia on the chronic post-thoracotomy pain.Int J Clin Exp Med. 2015; 8: 8101-8107
- Analgesia in thoracic surgery: Review.Minerva Anestesiol. 2009; 75: 393-400
- A comparison of the analgesia efficacy and side effects of paravertebral compared with epidural blockade for thoracotomy: an updated meta-analysis.PLoS One. 2014; 9: e96233
- Mitigating the impact of acute and chronic post-thoracotomy pain.J Cardiothorac Vasc Anesth. 2014; 28: 1048-1056
- Considerations for extrapolating evidence of acute and chronic pain analgesic efficacy.Pain. 2011; 152: 1705-1708
- Symptom recovery after thoracic surgery: Measuring patient-reported outcomes with the MD anderson symptom inventory.J Thorac Cardiovasc Surg. 2015; 150: 613-619.e612
- Efficacy of wound analgesia for controlling post-thoracotomy pain: a randomized double-blind study.Eur J Cardiothorac Surg. 2016; 49: 339-347
- Thoracoscopy versus thoracotomy: a prospective comparison of trauma and quality of life.Langenbecks Arch Surg. 2002; 387: 32-36
- Thoracotomy and thoracoscopy: postoperative pulmonary function, pain and chest wall complaints.Eur J Cardiothorac Surg. 1997; 12: 82-87
- A method of assessing reasons for conversion during video-assisted thoracoscopic lobectomy.Interact Cardiovasc Thorac Surg. 2011; 12: 962-964
- Validation of the critical-care pain observation tool in adult patients.Am J Crit Care. 2006; 15: 420-427
- Postthoracotomy pain management problems.Anesthesiology clin. 2008; 26 (vii): 355-367
- Transition from acute to chronic pain after surgery.Lancet. 2019; 393: 1537-1546
- Preventing and treating pain after thoracic surgery.Anesthesiology. 2006; 104: 594-600
- A randomized, double-blind trial comparing continuous thoracic epidural bupivacaine with and without opioid in contrast to a continuous paravertebral infusion of bupivacaine for post-thoracotomy pain.J Cardiothorac Vasc Anesth. 2012; 26: 83-89
- Guidance for Industry Analgesic Indications: Developing Drug and Biological Products. U.S. Department of Health and Human Services Food and Drug Administration Center for Drug Evaluation and Research (CDER).Office of Communications, Division of Drug Information Center for Drug Evaluation and Research, Silver Spring, MD2014.
- Regional versus systemic analgesia in video-assisted thoracoscopic lobectomy: A retrospective analysis.BMC Anesthesiol. 2019; 19: 183
- Chest drain size: the debate continues.Curr Pulmonol Rep. 2017; 6: 26-29
- The association between incentive spirometry performance and pain in postoperative thoracic epidural analgesia.Reg Anesth Pain Med. 2015; 40: 232-238
- Acute and chronic pain syndromes after thoracic surgery.Surg Clin North Am. 2002; 82: 849-865
Health NI: NIH Common Data Elements (CDE) Resource Portal. https://datascience.nih.gov/sites/default/files/NIH_Strategic_Plan_for_Data_Science_Final_508.pdf
- Pain assessment in the nonverbal patient: position statement with clinical practice recommendations.Pain management nursing: off j Am Soc of Pain Management Nurses. 2006; 7: 44-52
- Thoracoscopic pulmonary wedge resection without post-operative chest drain: An observational study.Gen Thorac Cardiovasc Surg. 2016; 64: 612-617
- Postthoracotomy pain syndrome following surgery for lung cancer: symptoms and impact on quality of life.J Adv Pract Oncol. 2015; 6: 121-132
- Efficacy and safety of paravertebral block versus intercostal nerve block in thoracic surgery and breast surgery: A systematic review and meta-analysis.PLoS One. 2020; 15e0237363
- Predictors of postoperative pain and analgesic consumption: A qualitative systematic review.Anesthesiology. 2009; 111: 657-677
- Causes of increased length of hospitalization on a general thoracic surgery service: A prospective observational study.Can J Surg. 2002; 45: 264-268
- Comparison between continuous thoracic epidural and paravertebral blocks for postoperative analgesia in patients undergoing thoracotomy: Systematic review.Braz J anesthesiol (Elsevier). 2013; 63: 433-442
- Independent predictors for higher postoperative pain intensity during recovery after open thoracic surgery: A retrospective analysis in 621 patients.Pain Med. 2017; : 1-7
- The ACTTION-APS-AAPM pain taxonomy (AAAPT) multidimensional approach to classifying acute pain conditions.Pain Med. 2017; 18: 947-958
- The ACTTION-APS-AAPM pain taxonomy (AAAPT) diagnostic criteria for acute pain conditions: An introduction.The j pain: off j Am Pain Soc. 2019;
- Changes in pulmonary function in lung cancer patients after video-assisted thoracic surgery.Ann Thorac Surg. 2015; 99: 210-217
- Preoperative gabapentin for acute post-thoracotomy analgesia: A randomized, double-blinded, active placebo-controlled study.Pain practice: the off j World Institute of Pain. 2012; 12: 175-183
- Evaluation of acute and chronic pain outcomes after robotic, video-assisted thoracoscopic surgery, or open anatomic pulmonary resection.J Thorac Cardiovasc Surg. 2017; 154: 652-659.e1
- Transition from acute to chronic pain after surgery.Pain. 2017; 158: S50-S54
- Analysis of 11 trials comparing muscle-sparing with posterolateral thoracotomy.Thorac Cardiovasc Surg. 2014; 62: 344-352
- Quality of life following lung cancer resection: Video-assisted thoracic surgery vs thoracotomy.Chest. 2002; 122: 584-589
- Thoracic surgery in the elderly.J Am Coll Surg. 2004; 199: 773-784
- Randomized double-blind comparison of phrenic nerve infiltration and suprascapular nerve block for ipsilateral shoulder pain after thoracic surgery.Eur J Cardiothorac Surg. 2011; 40: 106-112
- Video-assisted thoracic surgery lobectomy: Experience with 1,100 cases.Ann Thorac Surg. 2006; 81 (discussion 425-426): 421-425
- Analgesia and pulmonary function after lung surgery: is a single intercostal nerve block plus patient-controlled intravenous morphine as effective as patient-controlled epidural anaesthesia? A randomized non-inferiority clinical trial.Br J Anaesth. 2011; 106: 580-589
- Pain after thoracotomy.BJA Education. 2015.; 16: 1-7
- The validation of a no-drain policy after thoracoscopic major lung resection.Ann Thorac Surg. 2017; 104: 1005-1011
- Pulmonary function, postoperative pain, and serum cytokine level after lobectomy: A comparison of VATS and conventional procedure.Ann Thorac Surg. 2001; 72: 362-365
- Pain ITftCoC. The IASP classification of chronic pain for ICD-11: Chronic primary pain.Pain. 2019; 160: 28-37
- Impact of acute pain and its management for thoracic surgical patients.Thorac Surg Clin. 2005; 15: 105-121
- Pain and physical function are similar following axillary, muscle-sparing vs posterolateral thoracotomy.Chest. 2005; 128: 2664-2670
- Women suffer more short and long-term pain than men after major thoracotomy.Clin J Pain. 2006; 22: 491-498
- Comparison of the single or double chest tube applications after pulmonary lobectomies.Eur J Cardiothorac Surg. 2009; 35 (discussion 35-36): 32-35
- Arendt-Nielsen L. Effect of pre-emptive ketamine on sensory changes and postoperative pain after thoracotomy: comparison of epidural and intramuscular routes.Br J Anaesth. 2004; 93: 356-361
- Risk factors for postoperative anxiety and depression after surgical treatment for lung cancerdagger.Eur J Cardiothorac Surg. 2016; 49: e16-e21
- Economic and humanistic burden of post-trauma and post-surgical neuropathic pain among adults in the United States.J Pain Res. 2013; 6: 459-469
- Effect of indomethacin on pain relief after thoracotomy.Br J Anaesth. 1990; 65: 624-627
- Delayed recovery following thoracic surgery: Persistent issues and potential interventions.Curr Opin Anaesthesiol. 2019; 32: 3-9
- Gender aspects in postoperative pain.Curr Opin Anaesthesiol. 2015; 28: 546-558
- Chronic post-thoracotomy pain: A retrospective study.Acta Anaesthesiol Scand. 2006; 50: 804-808
- Protective effects of epidural analgesia on pulmonary complications after abdominal and thoracic surgery: A meta-analysis.Arch Surg. 2008; 143 (discussion 1000): 990-999
- Intraoperative conversion from video-assisted thoracoscopic surgery lobectomy to open thoracotomy: A study of causes and implications.J Thorac Cardiovasc Surg. 2015; 149 (62 e51): 55-61
- Effect of opioids vs NSAIDs and larger vs smaller chest tube size on pain control and pleurodesis efficacy among patients with malignant pleural effusion: The TIME1 randomized clinical trial.JAMA. 2015; 314: 2641-2653
- The impact of chest tube removal on pain and pulmonary function after pulmonary resection.Eur J Cardiothorac Surg. 2012; 41 (discussion 823): 820-822
- A prospective trial comparing pain and quality of life measures after anatomic lung resection using thoracoscopy or thoracotomy.Ann Thorac Surg. 2014; 98: 1160-1166
- Demographic and psychosocial predictors of acute perioperative pain for total knee arthroplasty.Pain research & management: the j Canadian Pain Soc = j de la societe canadienne pour le traitement de la douleur. 2007; 12: 185-194
- Postoperative complications after thoracic surgery for lung cancer.Clin Imaging. 2015; 39: 735-749
- Symptom severity 1 to 4 months after thoracotomy for lung cancer.Am J Crit Care. 2008; 17 (quiz 468): 455-467
- Predicting poor postoperative acute pain outcome in adults: An international, multicentre database analysis of risk factors in 50,005 patients.Pain reports. 2020; 5: e831
- Can chronic neuropathic pain following thoracic surgery be predicted during the postoperative period?.Interact Cardiovasc Thorac Surg. 2009; 9: 999-1002
- Effect of celecoxib combined with thoracic epidural analgesia on pain after thoracotomy.Br J Anaesth. 2010; 105: 196-200
- The effects of three different analgesia techniques on long-term postthoracotomy pain.Anesth Analg. 2002; 94: 11-15
- [Early chest tube removal after video-assisted thoracoscopic surgery. Results of a prospective randomized study].Chirurg. 2005; 76: 1155-1160
- Pre-emptive local anesthesia for needlescopic video-assisted thoracic surgery: a randomized controlled trial.Eur J Cardiothorac Surg. 2007; 31: 103-108
- The prevalence of postoperative pain in a sample of 1490 surgical inpatients.Eur J Anaesthesiol. 2008; 25: 267-274
- Systematic review of movement-evoked pain versus pain at rest in postsurgical clinical trials and meta-analyses: a fundamental distinction requiring standardized measurement.Pain. 2011; 152: 1734-1739
- Only half of the chronic pain after thoracic surgery shows a neuropathic component.The j pain: off j Am Pain Soc. 2008; 9: 955-961
- Regional analgesia for video-assisted thoracic surgery: a systematic review.Eur J Cardiothorac Surg. 2014; 45: 959-966
- Long-term benefits for the quality of life after video-assisted thoracoscopic lobectomy in patients with lung cancer.Surg Laparosc Endosc Percutan Tech. 1999; 9: 403-408
- Opioid therapy for chronic pain in the United States: Promises and perils.Pain. 2013; 154: S94-100
- Suprascapular nerve block for ipsilateral shoulder pain after thoracotomy with thoracic epidural analgesia: a double-blind comparison of 0.5% bupivacaine and 0.9% saline.Anesth Analg. 2002; 94 (table of contents): 199-202
- Perioperative epidural or intravenous ketamine does not improve the effectiveness of thoracic epidural analgesia for acute and chronic pain after thoracotomy.Clin J Pain. 2014; 30: 490-500
- The: Society of Thoracic Surgeons General Thoracic Surgery Executive Summary.The Society for Thoracic Surgeons, 2018
- No drain after thoracoscopic major lung resection for cancer helps preserve the physical function.Ann Thorac Surg. 2019; 108: 399-404
- The evolution of intraoperative conversion in video assisted thoracoscopic lobectomy.Ann R Coll Surg Engl. 2017; 99: 129-133
- Estimating hospital costs attributable to prolonged air leak in pulmonary lobectomy.Eur J Cardiothorac Surg. 2005; 27: 329-333
- Are intracostal sutures better than pericostal sutures for closing a thoracotomy?.Interact Cardiovasc Thorac Surg. 2012; 14: 807-815
- Enhanced presurgical pain temporal summation response predicts post-thoracotomy pain intensity during the acute postoperative phase.The j pain: off j Am Pain Society. 2009; 10: 628-636
- Prediction of postoperative pain: a systematic review of predictive experimental pain studies.Anesthesiology. 2010; 112: 1494-1502
- Late sensory changes following chest drain insertion during thoracotomy.Acta Anaesthesiol Scand. 2013; 57: 776-783
- A prospective study examining the impact of uniportal video-assisted thoracic surgery on the short-term quality of life in patients with lung cancer.Thorac Cancer. 2020; 11: 612-618
- Pre-emptive epidural analgesia improves post-operative pain and immune function in patients undergoing thoracotomy.ANZ J Surg. 2015; 85: 472-477
- Prediction of chronic post-operative pain: pre-operative DNIC testing identifies patients at risk.Pain. 2008; 138: 22-28
- Paravertebral block versus thoracic epidural for patients undergoing thoracotomy.Cochrane Database Syst Rev. 2016; 2Cd009121
- Postthoracotomy ipsilateral shoulder pain: A literature review on characteristics and treatment.Pain Res Manag. 2016; 20163652726
Article info
Publication history
Published online: April 10, 2021
Footnotes
Funding: This work was supported by the ACTTION partnership.
Conflicts of Interest: The authors declare no competing interests.
Identification
Copyright
© 2021 by United States Association for the Study of Pain, Inc.