Highlights
- •Preliminary results support the use of the Pedi-Sense to evaluate mechanical allodynia.
- •Test-retest and interrater reliability of the Pedi-Sense still need to be studied.
- •Participants appeared to report improved allodynia on the Pedi-Sense after IIPT.
Abstract
Youth with complex regional pain syndrome (CRPS) commonly experience mechanical allodynia
and disability. Assessment of mechanical allodynia is typically binary (present or
absent), making it difficult to assess the quality and degree of mechanical allodynia
before and after treatment. This study developed and validated the Pediatric Tactile
Sensitivity Test of Allodynia (Pedi-Sense) to provide an easy way for rehabilitation
clinicians to evaluate mechanical allodynia before and after intensive interdisciplinary
pain treatment. The 6 Pedi-Sense items demonstrated adequate internal consistency
reliability (CR) at admission (CR = .956) and discharge (CR = .973), reasonably fit
the hypothesized linear model of stimulus intensity (P < .0001), and significantly loaded onto a single latent factor, mechanical allodynia
(P < .0001), at admission and discharge. Pedi-Sense scores significantly correlated
with disability (rs = .40; P = .004) and pain catastrophizing (rs = .33; P = .017) at admission. The Pedi-Sense appeared responsive to intervention as participants’
total scores improved by 1.44 points (95% CI: .72, 2.15) after IIPT interventions
that included daily tactile desensitization. However, test-retest and interrater reliability
and the specific contribution of desensitization treatment to the overall success
of multi-modal pain rehabilitation still needs to be evaluated.
Perspective
This article presents the development and preliminary validation of a novel clinical
assessment of static and dynamic mechanical allodynia. The Pediatric Tactile Sensitivity
Test of Allodynia (Pedi-Sense) allows rehabilitation clinicians to easily evaluate
mechanical allodynia at the bedside with minimal training and simple equipment to
guide desensitization treatment in clinical settings.
Key words
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Article info
Publication history
Published online: December 29, 2022
Accepted:
December 17,
2022
Received in revised form:
December 6,
2022
Received:
August 12,
2022
Publication stage
In Press Journal Pre-ProofFootnotes
This work was conducted with support from Harvard Catalyst | The Harvard Clinical and Translational Science Center (National Center for Research Resources and the National Center for Advancing Translational Sciences, National Institutes of Health Award UL1 TR001102) and financial contributions from Harvard University and its affiliated academic healthcare centers. The content is solely the responsibility of the authors and does not necessarily represent the official views of Harvard Catalyst, Harvard University and its affiliated academic healthcare centers, or the National Institutes of Health. There are no other funding sources or conflicts of interest to disclose.
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© 2022 by United States Association for the Study of Pain, Inc.
