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10th Anniversary Articles

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Critical Review
How Neuroimaging Studies Have Challenged Us to Rethink: Is Chronic Pain a Disease?
The Journal of Pain
Vol. 10Issue 11p1113–1120Published in issue: November, 2009
- Irene Tracey
- M. Catherine Bushnell
Cited in Scopus: 330
In this review, we present data from functional, structural, and molecular imaging studies in patients and animals supporting the notion that it might be time to reconsider chronic pain as a disease. Across a range of chronic pain conditions, similar observations have been made regarding changes in structure and function within the brains of patients. We discuss these observations within the framework of the current definition of a disease.